Strategy management Essay Example | Topics and Well Written Essays - 3000 words

Procedure the board - Essay Example Over the timeframe, it has followed a forceful development system and turned out to be progressively creative contribution extra administrations. It has additionally been one of the main worldwide retailers on the planet to offer versatile installment checkouts at its few of stores. Through it has followed a forceful system to additionally enter into its current markets; it has likewise been increasingly forceful as far as market improvement and has been opening its outlets in different new markets. Starbucks has in excess of 700 stores in UK, it is working to be one of the main espresso producers in the nation. UK is experiencing a financial downturn and generally speaking shopper certainty is moderately low. It was a direct result of this explanation that Starbucks endured misfortunes in UK likewise in any case; it is as yet recuperating and is following a forceful procedure to infiltrate into UK advertise. Large scale Environment Analysis The fundamental variables talked about in this examination are significant on the grounds that it straightforwardly impact the way Starbucks works in UK showcase. A cautious administration of these variables requires successful vital activity so as to turn out to be increasingly serious in the market. Political Factors UK is considered as the mother of popular government on the planet with stable government set up. Government is strong of market economies and is in this way the general danger of government mediation is moderately careless. By and large government strategies are positive for the private ventures and the private property rights and laws are appropriately in set. Despite the fact that UK has solid organization set up in any case, government organization and functionaries are steady of private ventures with minimal authoritative obstacles set up. In spite of the fact that UK has a past filled with nationalizing privately owned businesses anyway it may not be the situation thinking about the general elements of worldwide business. Financial Factors UK is experiencing monetary downturn with reliably low or negative financial development rates saw during most recent couple of years. Joblessness is on the ascent and government has set up severity measures to control government consumption. Because of these components, in general shopper certainty is low and buyers are pulling back their utilization to spare more. As of late, UK economy experienced somewhat higher monetary development rates because of Olympics be that as it may, this might be considered as an occasional variety. (Monaghan, 2012).â Still the degree of joblessness is generally with in excess of 2 million individuals are as yet jobless. With the economy further contracting, it might be conceivable that the joblessness rates may increment. Social Factors Drinking espresso is turning into a standard in UK however Britain are considered as tea consumers. For the most part regular workers experts just as youth like to drink espress o and is progressively turning into an accepted practice in UK. It has additionally been proposed that drink espresso is considered as something which high achievers do. Espresso, socially, is being smashed by the working experts who are searching for some in a hurry brag of vitality. Espresso is additionally being utilized in workplaces for the most part with various associations. Innovative Factors Technology is generally changing quick with portable installments turning out to be new patterns for purchasers to paying. The progression in advanced mobile phones and portable installments innovation has gotten new changes the manner in which customers really connect and pay. The effect of online proposals in transit

Shirley Jackson Study Guide free essay sample

Presentation a. Snare: It isn't in every case genuine that with age comes astuteness. b. Lead: In Shirley Jackson’s short stories, â€Å"Afternoon in Linen† and â€Å"After You My Dear Alphonse† the kids show insight by not acting better than others around them. c. Postulation: In â€Å"Afternoon in Linen† and â€Å"After You My Dear Alphonse† Shirley Jackson utilizes comparative portrayals and incongruity to make this subject. II. BP 1 a. Point An intolerant individual regularly decides not to allow free realities when an idea is planted in their mind. b. Portrayal: Mrs. Wilson is biased . Models I. Expect that Johnny made Boyd convey all the wood since he is African American ii. Accept Boyd’s father is a worker in the processing plant iii. Expect his mom would work iv. Accept he doesn't eat well v. Accept he needs garments vi. Accept he has numerous siblings and sisters d. We will compose a custom article test on Shirley Jackson Study Guide or on the other hand any comparative subject explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page Finishing up Mrs. Wilson was determined to the possibility that in light of the fact that Boyd was African American he was poor. Significantly subsequent to being told more than once she wasn't right she kept on pushing and push. III. BP 2 a. Theme Showing off scarcely ever ends up being great. b. Portrayal: Harriet’s grandma, Ms. Lennon, is intolerant c. Models I. Discusses how her granddaughter plays constantly ii. Gets resentful when Harriet won’t play music and pushes her to peruse her sonnets iii. Continues pushing and pushing in any event, when Harriet continues denying iv. Doesn’t acknowledge what Harriet is doing and doesn’t care since she needs to flaunt so seriously d. Finishing up Ms. Lennon attempted to flaunt Harriet yet Harriet would prefer to be viewed as a literary thief than flaunt. IV. BP 3 a. Point When an individual is persuaded they are correct it’s difficult to convince them in any case. b. Incongruity: Mrs. Wilson acts far and away more terrible to Boyd when she understands he doesn’t need her assistance c. Models I. When Boyd continues denying her endeavors at greatness, she really shows what is a greater amount of her genuine character â€thinking she is better than others d. Finishing up When Mrs. Wilson try’s to help Boyd thinking he is poor since he is African American she harms urges others to view her ominously. V. BP 4 a. Theme A child’s determination can defeat a grandparents intensity. b. Incongruity: Harriet would prefer to be viewed as a literary thief than feed into her grandmother’s want to be superior to the Kator’s c. Models I. Harriet denies doing anything for the grandma and really deceives make herself look downright awful just with the goal that the grandma can't act better than the Kator’s d. Closing Harriet’s determination defeated her grandmas intensity. VI. Determination a. The utilization of incongruity and portrayal are compelling in making a subject b. Shirley Jackson’s short stories, â€Å"Afternoon in Linen† and â€Å"After You My Dear Alphonse† exhibit the subject that kids are more savvy than grown-ups on the grounds that they have not let the shades of malice of society sway them yet. c. The virtue of a kid ought to be utilized as a model for the grown-ups of society.

Cost Analysis Essay Example | Topics and Well Written Essays - 750 words

Cost Analysis - Essay Example 6 Works refered to 8 1. What amount do US Airways benefits vary because of fuel instability? The quarterly report of 2013 of US Airways shows that, when contrasted with 2012, the net gain earned by the organization in the second quarter of 2013 has diminished, which has additionally brought down the Earnings per Share (EPS) accessible to the investors. The purpose behind this abatement in benefits can be allocated to the unpredictability in costs of fuel. As referenced in the quarterly report of 2013, every day the costs of Brent unrefined petroleum had vacillated between $110 per barrel to $97 per barrel in the long stretch of April, and in the quarter end the cost was seen as $102 per barrel. In spite of the fact that the U.S. carrier Industry is confronting moderate fuel costs in the second quarter of 2013, however in the first quarter of 2012, the business confronted higher unpredictability and vulnerability which have influenced the business. The vulnerability in the costs of fu el has caused interruptions in the flexibly of airplane fuel and has antagonistically influenced the working outcomes and liquidity of the organization. 2.  Why is fuel unpredictability terrible for benefits? Do a cost examination alone, and afterward do a full benefit augmenting investigation. Instability in the costs of fuel has genuine effects on benefits of the organization. The unpredictability results in good and bad times in profits and offer costs which unfavorable influences worldwide development. Instability in the costs of fuel likewise influences yield, activities and income, which thus influences gainfulness. The expense of communicate and mainline fuel was $1.13billion in the second quarter of 2013, which was 4.6% or $55million lower when contrasted with the second quarter of 2012. The organization is attempting to keep up a minimal effort structure, yet it is reliant on two factors, the wellbeing of the economy and the cost of fuel. The mainline costs per accessible seat mile barring exceptional things, fuel and benefits have diminished by 0.4%, for example 0.04cents, from 8.25cents in the second quarter of 2012, to 8.21cents in the second quarter of 2013. In such a circumstance, the organization can endeavor to augment its benefits by an endeavor to limit its dangers by receiving hazard control measures. Precise hazard isn't heavily influenced by the organization, however the organization may attempt to beat unsystematic dangers with the assistance of key choices. 3. What is Express Operation’s working expense per ASM? What is its working expense per RPM? What is the contrast between these two numbers? Cost per Available Seat Miles (CASM) is a proportion of unit cost utilized ordinarily in the carrier business. It is communicated in pennies to deal with each seat mile advertised. It is figured by separating different proportions of working income by ASM (Available Seat Miles). Cost per ASM is utilized to analyze expenses of various car riers or of a similar aircraft across various timespans. A lower CASM makes it simpler for a carrier to make benefit, yet doesn't ensure productivity. Income Passenger Mile (RPM) is made when a traveler pays to fly one mile and is viewed as the fundamental proportion of aircraft traveler traffic. RPM can be viewed as the essential measure of creation made by an aircraft. RPM can be determined by duplicating the quantity of filled seats by the quantity of miles flown. Over an airline’s framework ASM can be contrasted with RPM to decide the all out traveler load factor. RPM is often contrasted with ASM, as ASM decides the complete number of traveler miles that could be created to confirm the measure of income

Free Essays on Dead Man Walking

Dead Man Walking The film â€Å"Dead Man Walking† raised some significant inquiries. Questions concerning moral, abhor, love, absolution, equity, and compromise. As well as though capital punishment is a proper and only discipline for a wrongdoing. All through this film there was a great deal of abhor. There was so much annoyance and demeanor in the entirety of the characters. Matt Poncelet was a befuddled and contemptuous person. He was so conceal with outrage that he didn’t even truly comprehend what his genuine sentiments were. He thought he was this huge, terrible, extreme individual yet he truly wasn’t. Inside he was a terrified little kid. He accepted that he was invulnerable and that nobody could contact him. It wasn’t until the end when he was in his cell anticipating his demise that he truly took ownership of what he was and the things that he did. The guardians of the two casualties were likewise loaded up with despise and outrage. They despised their children’s executioners, however who wouldn’t loathe the enemies of your kinfolk. They were blinded by their detest. All they needed was to see the man that slaughtered their kids dead. It appears to me that detest was the primary driver for the entirety of the issues in the film. In some cases individuals need to simply unwind and allow things to occur. Scorn is an ailment that murders. Contempt executed the children, disdain murdered Mathew Poncelet, and scorn slaughtered the marriage of the casualties guardians. Abhor makes individuals anxious, they hop and detonate at the smallest thing. Abhor in unfortunate, it consumes within you and gets to your character. Abhor changes individuals for the more awful. Individuals need to figure out how to pardon others for their activities. The guardians of the casualties didn’t fundamentally need to excuse Matt Poncelet yet they expected to let it proceed to have him get his discipline. They expected to comprehend that in any event, when he was executed it would not bring back their kids. It might cause them to feel better be that as it may, it despite everything wont transform anything. Everything will in any case be... Free Essays on Dead Man Walking Free Essays on Dead Man Walking Dead Man Walking The film â€Å"Dead Man Walking† raised some significant inquiries. Questions concerning moral, detest, love, absolution, equity, and compromise. As well as though capital punishment is a proper and only discipline for a wrongdoing. All through this film there was a great deal of detest. There was so much outrage and aura in the entirety of the characters. Matt Poncelet was a confounded and disdainful person. He was so covered with outrage that he didn’t even truly recognize what his genuine emotions were. He thought he was this huge, terrible, extreme individual however he truly wasn’t. Inside he was a frightened little kid. He accepted that he was strong and that nobody could contact him. It wasn’t until the end when he was in his cell anticipating his demise that he truly took ownership of what he was and the things that he did. The guardians of the two casualties were additionally loaded up with despise and outrage. They loathed their children’s executioners, yet who wouldn’t despise the enemies of your family. They were blinded by their detest. All they needed was to see the man that slaughtered their kids dead. It appears to me that detest was the primary driver for the entirety of the issues in the film. In some cases individuals need to simply unwind and allow things to occur. Scorn is a malady that executes. Disdain murdered the children, scorn executed Mathew Poncelet, and contempt slaughtered the marriage of the casualties guardians. Despise makes individuals tense, they bounce and detonate at the smallest thing. Abhor in undesirable, it destroys within you and gets to your character. Abhor changes individuals for the more regrettable. Individuals need to figure out how to excuse others for their activities. The guardians of the casualties didn’t fundamentally need to excuse Matt Poncelet however they expected to let it proceed to have him get his discipline. They expected to comprehend that in any event, when he was executed it would not bring back their kids. It might cause them to feel better in any case, it despite everything wont transform anything. Everything will in any case be...

Developing Marketing Strategies and Plans MCQS Essay

1. A key element of the showcasing the executives procedure is sagacious, ________ advertising methodologies and plans that can manage promoting exercises. a. imaginative b. quantifiable c. large scale d. smaller scale e. specialty Answer: a 2. As per a part tale about H&M garments stores, H&M can put items out rapidly and reasonably by the entirety of the accompanying EXCEPT ________. a. having not many mediators and possessing no industrial facilities b. purchasing enormous volumes c. having broad involvement with the attire business d. having an incredible information on which merchandise ought to be purchased from which markets e. having complete control of its dispersion channel from the time the merchandise are delivered until the time they are sold Answer: e 3. The undertaking of any business is to convey ________ at a benefit. a. client needs b. items c. client esteem d. items and administrations e. improved quality Answer: c 4. In a hyper serious economy, for example, our own, an organization can win just by tweaking the worth conveyance process and picking, giving, and ________ unrivaled worth. a. conveying b. choosing objective markets with c. making d. creating e. examining Answer: a 5. The customary perspective on showcasing is that the firm makes something and afterward ________ it. a. markets b. sells c. disseminates d. costs e. administrations Answer: b 6. Today, the â€Å"mass-market† is really fragmenting into various ________, each with its own needs, discernments, inclinations, and purchasing standards. a. smaller scale markets b. showcase targets c. full scale markets d. client inner circles e. segment units Answer: a 7. The primary period of the worth creation and conveyance arrangement is ________ that speaks to the â€Å"homework† promoting must do before any item exists. a. picking the worth b. statistical surveying c. target showcasing d. administration thought e. projective reasoning Answer: a 8. The last advance in the worth creation and conveyance arrangement is ________ the worth where the business power, deals advancement, publicizing, and other specialized apparatuses declare and advance the item. a. creating b. conveying c. conveying d. turning around e. investigating Answer: c 9. The Japanese have refined the worth conveyance procedure to incorporate a part that underscores ________. a. zero overhauling b. zero client input time c. zero advancement d. zero reliance on middle people e. zero showcasing costs Answer: b 10. The ________ is an instrument for distinguishing approaches to make more client esteem. a. esteem chain b. client review c. brand steadfastness file d. advancement channel e. provider database Answer: a 11. The ________ recognizes nine deliberately significant exercises that make worth and cost in a particular business. a. offer b. esteem chain c. statement of purpose d. yearly report e. manager’s log Answer: b 12. The ________ in the worth chain spread the arrangement of carrying materials into the business (inbound coordinations), changing over them into definite items (tasks), transporting out conclusive items (outbound coordinations), promoting them (advertising and deals), and overhauling them (administration). a. activities process b. fabricating process c. essential exercises d. optional exercises e. tertiary exercises Answer: c 13. Obtainment, innovation improvement, human asset the board, and firm framework are dealt with in certain specific offices and are called ________. a. materials taking care of b. bolster exercises c. stock exercises d. essential exercises e. benchmark exercises Answer: b 14. The firm should assess its competitors’ expenses and exhibitions as ________ against which to look at its own expenses and execution. a. rivalry b. norms c. challenges d. benchmarks e. moveable norms Answer: d 15. The firm’s achievement depends not just on how well every office plays out its work, yet additionally on how well the different departmental exercises are facilitated to lead ________. a. center methodologies b. satellite organizations c. guiding principle d. center business forms e. center advancements Answer: d 16. As for center business forms, all the exercises associated with social event showcase insight, dispersing it inside the association, and following up on the data is alluded to as the ________. a. showcase detecting process b. statistical surveying process c. target promoting process d. showcase beat process e. organization process Answer: a 17. As for the center business forms, all the exercises associated with exploring, creating, and propelling new top notch contributions rapidly and inside spending plan are alluded to as the ________. a. new item process b. new contribution acknowledgment process c. item improvement process d. item dispatch process e. quantifiable profit process Answer: b 18. As for the center business forms, the ________ is viewed as all the exercises engaged with characterizing objective markets and prospecting for new clients. a. client procurement process b. client relationship the board procedure c. satisfaction the board procedure d. client prospecting process e. client value process Answer: a 19. A decent method to portray the ________ would be examine all the exercises associated with building further getting, connections, and contributions to singular clients. a. client securing process b. client relationship the board procedure c. client prospecting process d. client satisfaction the executives procedure e. client value process Answer: b 20. Another approach to depict a worth conveyance arrange (banding together with explicit providers and merchants) is to consider it a ________. a. cooperation gathering b. plot c. local force community d. connection to connections e. flexibly chain Answer: e 21. The way to using hierarchical center skills is to ________ that make up the pith of the business. a. make the capabilities pay for themselves b. own all middle people who interact with your products and ventures c. own and sustain the assets and capabilities d. underscore worldwide advancements e. fragment workforces Answer: c 22. We can say that a ________ has three qualities: (1) It is a wellspring of upper hand in that it makes a huge commitment to saw client benefits, (2) it has applications in a wide assortment of business sectors, and (3) it is hard for contenders to impersonate. a. center competency b. business system c. center innovation d. vital specialty unit e. winning system Answer: a 23. Center abilities will in general allude to zones of extraordinary specialized and creation skill, where ________ will in general portray greatness in more extensive business forms. a. process benchmarks b. unmistakable capacities c. center business esteems d. esteem explanations e. statements of purpose Answer: b 24. George Day sees showcase driven associations as exceeding expectations in three unmistakable abilities: ________, client connecting, and channel holding. a. target advertising b. statistical surveying c. satisfying client needs d. showcase detecting e. client support connections Answer: d 25. Contenders think that its difficult to impersonate organizations, for example, Southwest Airlines, Dell, or IKEA in light of the fact that they can't duplicate their ________. a. item advancements b. appropriation system c. estimating arrangements d. action frameworks e. coordinations framework Answer: d 26. One origination of all encompassing showcasing sees it as â€Å"integrating the worth investigation, ________, and esteem conveyance exercises to fabricate long haul, commonly fulfilling relationship and co-thriving among key stakeholders.† a. esteem creation b. incentive c. esteem the board d. esteem explore e. esteem chain Answer: a 27. All encompassing advertisers accomplish beneficial development by growing client share, ________, and catching client lifetime esteem. a. subverting serious abilities b. building client steadfastness c. draining the market for item wants d. restoring a client base e. examining all piece of the overall industry information Answer: b 28. The all encompassing advertising system is intended to address three key administration questions. Which of coming up next would one say one is of those inquiries? a. Worth claimsâ€how does the organization manage esteem disintegration? b. Worth propositionâ€how can offers be made beneficial? c. Worth chainâ€are there powerless connections in the company’s esteem chain d. Worth networkâ€how can an organization adequately arrange? e. Worth explorationâ€how can an organization distinguish new worth chances? Answer: e 29. The customer’s ________ reflects existing and inert needs and incorporates measurements, for example, the requirement for cooperation, steadiness, opportunity, and change. a. ability space b. asset space c. enthusiastic space d. relationship space e. intellectual space Answer: e 30. The organizations ________ can be depicted as far as breadthâ€broad versus centered extent of business; and depthâ€physical versus information based capacities. a. business crucial b. center methodology c. subjective space d. competency space e. asset space Answer: d 31. The collaborator’s ________ includes even organizations, where organizations pick accomplices dependent on their capacity to abuse related market openings, and vertical association, where organizations pick accomplices dependent on their capacity to serve their worth creation. a. asset space b. competency space c. psychological space d. balanced space e. administration space Answer: a 32. Business realignment might be important to expand center abilities. Which of the accompanying would be one of the means in this realignment procedure? a. Investigating every large scale relationship. b. Inspecting worldwide effort projections. c. Rethinking the business idea (the â€Å"big idea†). d. Looking into triumphs from web based business (assuming any). e. Redoing the morals articulation. Answer: c 33. ________ permits the organization to find who its cust

The Value of Believing You Get What You Pay For

The Value of Believing You Get What You Pay For Choosing Value Last week I received a call from a marketing executive in Switzerland who wanted assistance with an important cover letter. He had found me on LinkedIn and chosen my company over three others. With excitement in his voice, he explained to me that as a marketer, he was fascinated by his own behavior in deciding upon The Essay Expert: He chose us because we were the most expensive company. In a similar phenomenon, for many months I had been frustrated that people were landing on my professional bio page and calling me about the service, but not purchasing. I considered removing bios from my offerings, but first decided to try raising my rates. Lo and behold, people started buying bios more often! I got the sense that they trusted they would get a better product and perhaps something they couldn’t write themselves. Of course, people do not always choose to buy the most expensive option in front of them. Different consumers have different budgets, and some people simply can’t afford to purchase more pricey goods and services. In fact, the same week I was contacted by the client from Switzerland, I also heard from a client who wanted to pay $500 for services that would normally go for $1700 according to my normal pricing. He simply could not afford my rates. And although I sympathized with his situation, I was not able to work with him and keep within my business model. Pricing Psychology If it’s true that “you get what you pay for,” expectations are set by price, and regardless of the actual product or service delivered, a consumer will value it according to what he or she paid for it. Studies have shown that people expect a positive correlation between price and quality (e.g., Rao and Monroe, 1989). In a 2008 study about wine enjoyment by Goldstein et. al., consumers who did not know the price of the wine they were drinking did not like more expensive wine better; but when they were told they were drinking a more expensive wine, they gave the wine higher ratings. It seems our brains actually play tricks on us to make us appreciate things more when we pay more money for them! This doesn’t mean that we can charge high prices and then deliver a shoddy result. If someone pays a high price for something and is disappointed, she might be even more upset than if she had paid lessâ€"although not necessarily! I have learned that people looking for a deal are often more demanding than those willing to pay for value. Choosing Clients My Swiss client was clearly guided by the phenomenon of expecting value for value. And he knew the value he wanted: the confidence that would come from having a clearly written, persuasive letter, in solid English, stating his commitment and qualifications for transitioning from the corporate to the non-profit world. He was my ideal client. He requested to pay a rush fee for a quick turnaround. He partnered with us fully in the project. And when we delivered the letter, he told us we had exceeded his expectations. In return, I was happy and willing to go the extra mile for him and give him the modifications he needed at 11pm U.S. Central time on a Friday night. He has already purchased additional services. The price-averse potential client, on the other hand, was not my ideal client. He presented with a complex situation that would have required more work than the average executive service, yet even at $1700 he would have been paying mid-level rates. Having been out of work for a year, I believe he was looking for a result that I could not guarantee: a job. For him, I believe confidence in putting his best foot forward might not have been enough, and I was concerned that he might come back asking for a refund of his $500. Every business owner when setting pricing must make a decision about what type of clients they want to target: Do you want those who are looking for a deal and will say yes because you offer one? Or those who want to pay for value and will appreciate your products and services in part because they paid top dollar for them? There is no right answer to which type of client to attract, but for me, I choose the latter. That’s my win-win and I am prepared to live up to my value proposition.

The Three Forms of Madness in King Lear - Literature Essay Samples

This essay concentrates on Act 111, Scene 4 of Shakespeares King Lear, a tragic and powerful scene in which we witness Lears mind tragically giving way to the menace of madness, which has relentlessly pursued him throughout the play. However, the character of Lear only portrays one of the three forms of madness represented in the scene he may be the only character who is truly mad, but there is also the feigned madness of Poor Tom, and the professional madness of the Fool. These varying forms of madness are all represented in different ways via varying styles and forms of language, imagery, movement and verbal styles.By the time that this scene takes place, Lear has been reduced from being a powerful and respected monarch with hundreds of followers, to being a lonely, rejected man, cast out of his own kingdom, his family, and all his fortune and wealth. He has been shut out in the night to wander the earth, accompanied by the only subjects whom remain loyal  ­ his Fool, and the Ea rl of Kent, who is disguised as Caius. The Fool and Kent have joined together in the scene to support the king, both physically and mentally.That Lear finds himself here is a mixture of the results of his own folly, and the cruelty that he suffers by the hands of his own flesh and blood. In the first scene of the play, Lear makes a series of mistakes, which ultimately prove fatal for the king. Firstly, he misguidedly casts off Cordelia, his only loyal daughter, then he proceeds to divide his kingdom between the two remaining pelican daughters (111.4.72), leaving himself with nothing but trust in his daughters love for him. However, as their title here suggests, his two daughters betray their doting fathers trust by seizing all power from him and uniting to place him in the wretched situation he now finds himself in.Even though Lear has been reduced to so little, his voice still remains the commanding one. He retains the language of the central figure, the hero of the play. He specia lises in hyperbole, inciting the stars at every given opportunity, including here, when he is cast out from his family and he commands the stars to cast down their diseases upon those that have caused him pain:Now all the plagues that in the pendulous air Hang fated oer mens faults light on thy daughters! (111.4.64-5)He conducts trials, ordering the wholly unqualified, but in Lears demented eyes, most learned justicer (111.6.21), Poor Tom, to be judge at the make-believe trial of Regan and Gonerill, he gives sermons, and he prays.Lears prayer in Act 111, Scene 4, shows him gaining his last firm foothold before his fall into the abyss of madness. As Danby claims, Lear has already learned humility and patience now he learns charity, (Danby 1948, p. 186) and also repentance of his  ³pomp ² (111.4. 33); Lear is oblivious to the physical damage such a tempest causes him, informing Kent that This tempest in my mind / Doth from my senses takes all feeling else / Save what beats there. (111.4.13-15), and so rather he prays for those others who are at the mercy of the gods and the storm. When he refers to himself, it is not to pray for his salvation, but to rebuke himself for the way he has lived his life, and to command himself to take physic, pomp (111.4.33) to become morally healthy by rejecting his old ways.When Lear prays, he is on a thin line between madness and sanity. A.C. Bradley questions, whether or not, had the king been allowed to sleep, as is his intention before the prayer, he would have actually made a return to health, as he does in Act 1V, Scene 7 (Bradley, 1948,287). As it is, this sleep and possible recovery is prevented by the arrival of Poor Tom, who bursts angrily into the scene, complete with curses and outbursts that team with his ghastly appearance to provide the catalyst that finally pushes Lear over the brink into madness.The sights and sounds of demented Poor Tom have an immediate effect on the king, sending him into a madness that is all the more tragic because of the contrast between himself only moments before, when he seems almost lucid, and his now wholly demented persona. Now he utters the first words of a truly mad king. His fall into madness is portrayed by the question, Didst thou give all to thy daughters? And art thou/ come to this? (111.4.47-48). His question sounds almost hopeful  ­ has he now found someone who is in the same plight as himself? Is he no longer alone in his suffering? The king cannot conceive that any thing or event could cause such pain and destitution as that which Poor Tom seems to suffer from, than ones own flesh and blood, ones daughters. He clutches to his idea and repeats it again and again (111.4.60-61, 64-69), refusing to listen to the futile voice of sanity and reason which manifests itself in the figure of Kent, who remains patient with the king throughout.The reason for Toms potent effect on the King is that the king has immediately identified with his pitiful situation . Lear has been cut off from his family, both because of his own folly in giving away his entire kingdom, and because of the treachery and deceitfulness of the two former daughters. He sees himself and his daughters as part of one body, a body that Regan and Gonerill have mutilated:Is it not as this mouth should tear this handFor lifting food tot? (111.4.16 -17)As he identified himself with his daughters, now that he has been cut (or bitten) off, he is lost  ­ he is desperate for someone to identify with, and in the meantime he flees from the madness that at every turn threatens to take hold of him, as he cries O, that way madness lies; let me shun that; / No more of that (111.4. 21 ­22). Tom, in the image of complete and utter human destitution, provides that someone that Lear is looking for.Lear, in his madness, has gained as well as lost. He does lose his dignity, identity, all the power and respect he was so used to commanding with Lear existing in a world where the ruler o f a country is, in authority, equal almost to God, his imperialism knew no bounds and was never questioned or resisted. Now his perception of reality has been completely overturned. But, as a result of this overturning, he has gained knowledge that he never possessed in sanity, learning truths that he could never before conceive. His way of thinking has been reversed he is no longer concerned with status or politics, as they are irrelevant to his new reality. He now sees past all the false flattery of his daughters and those around him, all the supposedly loyal servants, whom so readily deserted him, just like ants who have learned that theres no labouring ithe winter (11.4.66). He emerges slowly from the political world that he was so immersed in, and begins to see the importance of individual human life versus status, and as Danby argues, morality versus politics (Danby, 1948, p. 171) He is now in a world where the quality (11.4.91) of individual personality is what matters, and position has lost its meaning. Therefore, for Lear, Poor Tom provides an image of man exactly as he should be  ­ naked against the world, not cloaked in lies and falseness, with no protection against the elements and facing life exactly as he is:Thou owest the Worm no silk, the beast no hide, the sheep no wool, the Cat no perfume. Ha! Heres three ons are sophisticated. Thou art the thing itself! Unacommodated man is no More but such a poor, bare, forked animal as thou art. (111.4.100-104)Lear sees the beggar therefore as a learned Theban (111.4.150), someone who knows the secrets of life and nature better than he, and so Lear begins to question him, What is the cause of thunder? (111.4.147). Lear goes on a quest to share in his new mentors knowledge of the world, hence the tearing off of his clothes in an attempt to emulate him (111.4.105).Edgar has invented a persona to fit what was, in Shakespeares time, the stereotypical image of madness and despair. He incess antly talks of the foul fiend (111.4.44), the devil that supposedly haunted the maddened; he claims to have received the traditional Devil-given gifts of knives, halters and ratsbane (111.4.52-53); he claims to see the devil Flibberdigibbet when Gloucester enters, an accusation which perhaps reflects the rejected Edgars feelings towards his father at this point in the play. Also, he defends himself against Gloucesters derisory remark about the low caliber of his company (111.4.135) by replying that he is attended by no less than Modo and Mahu (111.4.136-7), grand commanders of legions of devils. He goes to great lengths to present a complex, cohesive and convincing image of himself and his existance, with his wild images of pursuing devils and his long-winded speech describing his past life, when there was little need to go to such lengths  ­ Lear is immediately taken in by his act, and the other characters are so busy being concerned with other events and troubles that they have little inclination to take heed of this mad vagrants rambling stories.Poor Toms physical appearance on stage would certainly convey the look of a poor beggar in utter destitution  ­ he is almost naked (111.4.62-3), and his physical wounds are indicated by Lears words, is it the fashion that discarded fathers/Should have thus little mercy on their flesh? referring, presumably, both to his nakedness and the wounds or scratches he has received as the result of this lack of protective clothing. However, despite this verbal and physical appearance, Poor Tom, in his madness, does not appear as tragic as Lear, for many reasons, the most obvious of which being that the audience knows it to be an act put on by the disguised Edgar. The audience feels pity only for Edgar, not for his manifestation of the Bedlam beggar (11.3.14). Also, a touch of humour in Poor Tom undermines his tragic circumstances  ­ for example, his imitation of a sailor navigating the deep, dark depths of the hovel his imaginary ship sails through. The cry of Fathom and half, fathom and half! (111.4.37), is not the cry of a soul in deepest torment from the foul fiend (111.4.43). Indeed, he seems to have an odd amount of energy for one so destitute.The Fool is another character who represents yet another form of madness  ­ professional madness. The Fool spends his life singing songs, riddles and rhymes ostensibly to entertain the king  ­ and in comparing the linguistic styles of the king and his sidekick Fool, we see how different the two characters positions are. While the King, so used to total authority, bellows at the stars, commanding them to do his bidding, the Fool whispers little ditties into his ear, speaking only to the person, not to the universe, which he rightfully comprehends, is out of his control. But the king would have done better to listen to this lowly Fool from the onset, for beneath the veil of nonsense, there lies an ocean of common sense. When the king rejects Cordelia , the Fool attempts to bombard Lear with this common sense in the only way his station in life allows him to  ­ through rhyme and riddle:There, take my coxcomb! Why, this Fellow has banished two ons daughters, and did the Third a blessing against his will. If thou follow him, thou Must needs wear my coxcomb. How now, nuncle! Would I have two coxcombs and two daughters! (1.4.99-105)Through looking carefully at the true meaning of his nonsense, we can see that the Fool is not mad he is in fact perhaps more sane than Lear ever was. He is yet another character in disguise, in a play filled with disguises. He constantly ironises the king, subtly mocking his actions and remarks with his comments, such as his sarcastic remark, Nay, he reserved a blanket; else we had been all / shamed (111.4.62-3), in reply to one of Lears confused questions. However, in this scene when the king loses his mind, we see the Fool slowly beginning to realise his impotence  ­ the king never before listened to his comments and advice, and he now lacks not just the inclination, but the ability to comprehend what he is being told, whether it be disguised as humour or not. The Fools realisation of the predicament the company is in is shown in his comment This cold night will turn us all to fools and mad- / men (111.4.75-6). Edgar has taken over the role of the Fool, the King is mad, and the Fool has become the balanced observer. The Fool remains loyal until he realises he can no longer fulfill any sort of purpose  ­ the king has gone mad, and no longer hears him. The only fool he will listen to is Poor Tom, and so the Fool takes his leave from the dialogue at the end of Act 111 Scene 6, with the words and Ill go to bed at noon (111.6.83)Kents patience and calm serves to highlight the madness all around him, whether it is the true madness of the king, Edgars feigned madness, or the professional madness of the Fool. He entreats his King to enter shelter a total of four times, never giving up on a man who did not listen to his sensibility at the beginning of the play, when he defends Cordelia, and even if he wished, he lacks the ability to listen now. Nevertheless, Kent stays with his master, sacrificing his own health to remain out in the metaphorical and physical storm with the king whom earlier ordered his banishment. Kent constantly tries to bring Lear back to reality, interjecting his outbursts with doses of sanity, such as when he tries to explain that Tom hath no daughters, sir (111.4.66). Unlike the Fool, whom soon realises the futility of efforts to communicate with the King and gives up, exiting the dialogue with the words And Ill go to bed at noon (111.6.83), Kent persists, and remains with the king until the very end of the play.Thus we can see that the three cases of madness which are portrayed in this scene all draw upon varying theatrical means to represent their different forms. Different styles of speech are used by each character, with Lears overst ating and the Fools realist comments on society, different aural effects and images portraying various outlooks on life, whether it be Toms vision of Hell, or Lears images of the heavens and their avenging stars (111.4.65). Through these contrasting styles of the characters in this scene, we witness the sanity of the professional madman, the comic Fool, and see how little the playacted madness of Poor Tom compares to the true and tragic pain endured by the tortured King Lear.

How Communication Skills Can Be Developed By Listening And...

Communication – Communication is perhaps the most looked for skill in an employee which involves elements such as being a productive listener, conveying yourself clearly as well as in writing, conveying messages to foreigners and depicting a clear and understandable case. Communication skills can be developed by listening and understanding information, speaking clearly and directly, familiarizing your writing to fit the criteria of the audience, negotiating, using numeracy accurately, creating your own network within the area you choose to surround yourself with, communicating (speaking and writing) in languages other than English, being able to sympathise and understand the needs of other people most importantly customers. Teamwork – Team work consists of communicating with others to establish a goal and achieve results as well as establishing the needs of other peoples thoughts and contribution ideas. You may have had an existing approach to teamwork if you have participated in team sports, part time jobs, even school or university activities. Teamwork skills are demonstrated effectively by working efficiently individually or as a team, working with people of different races, backgrounds, sexual preferences, religion or political influences, being able to adapt to different roles and responsibilities, being able to pin point certain positives or negatives of fellow team members and also open-handed criticism. Problem solving – Problem solving involves being able toShow MoreRelatedThe Importance Of Effective Communication For Different Social Groups And Use Specific Interpersonal Strategy1329 Words   |  6 Pagesdefinition of communication necessarily involves â€Å"an exchange of ideas and an ability to stimulate meaning for the recipient of the message†(Grover, 2005). 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Unfortunately, management at every level is experiencing increased tension andRead MoreSample Resume : Dentist Patient Communication1000 Words   |  4 PagesDentist–Patient Communication Good communication skills help dental care experts establish a good dentist–patient relationship (Mills et al., 2013). As such, many dental care programs – undergraduate and postgraduate – have made developing good communication skills mandatory through education and training (Hannah and Millichamp, 2004). The rise in demand for dentists who adopt a patient-centered approach, in addition to consumerism in the dental care profession, has culminated in the developmentRead MorePersonal Communication Analysis815 Words   |  4 PagesPersonal Communication Analysis Communication is vital in today’s society. The purpose of communication is to relay messages in the most clear and concise appropriate manner. Transferring data involves both the sender and receiver of a message. Communication can be misinterpreted, sent with confusion and often misrepresented. Effective communication is the key to getting messages across and with minimal confusion and errors.

How Morals Are Thrown Around Through The Actions And...

Andrew Robb In the tragedy â€Å"Antigone† many ideas of morals are tossed around through the actions and speeches of the characters Creon and Antigone. Though these morals seem logical at first, it can later be seen that these two characters represent an over fixation on singular ideas, or morals, of life when it is taken to the extreme. This close mindedness ultimately leads to these character’s downfalls with Creon revealing that his moral extreme is the â€Å"political sphere† of life and Antigone, the â€Å"private sphere† holds the truth. She wants to bury her brother, Polynices (Galens). A proper burial for those killed in battle was essential for the Ancient Greeks (Fletcher). To give Polynices his proper burial, she infringes upon her Uncle Creon s laws that specifically forbid her from burying Polynices as he was an enemy of the people. She wishes to follow and interpret the traditions and rituals the divine gods expect, and hence clashes with Cr eon s governmental status. Through focusing their entire lives to these causes and desires, they have damned themselves to their own demise by being so close-minded of the world around them. Creon is a fatigued, wrinkled man enduring the weights of leadership and has now surrendered himself altogether to the throne. Unlike Antigone, he has totally ceded his wishes to take upon the mantle of administration. As he tells Antigone, his only interest is in political and social order. This obsession with the state and civil order causes himShow MoreRelatedtheme of alienation n no where man by kamala markandeya23279 Words   |  94 Pagesï » ¿ANTIGONE KEY LITERARY ELEMENTS SETTING This tragedy is set against the background of the Oedipus legend. It illustrates how the curse on the House of Labdacus (who is the grandson of Cadmus, founder of Thebes, and the father of Laius, whose son is Oedipus) brought about the deaths of Oedipus and his wife-mother, Jocasta, as well as the double fratricide of Eteocles and Polynices. Furthermore, Antigone dies after defying King Creon. The play is set in Thebes, a powerful city-state north of

The Nature Of Military Power - 2256 Words

What is the nature of military power and how should it be used to serve national interests? These fundamental questions form the foundation of military strategy. Various answers developed by civilian and military theorists over the past century all center on the idea of controlling conflict by rationally applying military power to achieve a desirable outcome. However, as economic, social, and political contexts evolve, they redefine ideas about power, its utility, and its application. As a result of this reciprocal relationship, theories of strategy, itself an amorphous concept, change. Corbett’s Some Principle of Maritime Strategy, Slessor’s Air Power and Armies, Wylie’s Military Strategy: A General Theory of Power Control, and†¦show more content†¦Besides Mahan, the navy’s focus on decisive battle reflected the thinking of Continental strategic theorist Carl von Clausewitz. Corbett’s principles draw heavily upon Clausewitz, particul arly his emphasis on war being a continuation of policy XXX and the importance of correctly identifying the type of war in which a nation engaged XXX. Corbett’s use of Clausewitz was unique, since he was attempting to apply theories for land warfare to conflict at sea. Corbett attempted to apply concepts from land warfare to war upon the sea in an attempt to shape the thinking of his contemporaries. However, Corbett differed from Mahan and Clausewitz by deemphasizing the importance of fleet engagements in battles of annihilation. Instead, he focused on the necessity of maneuver to place the enemy at a disadvantage, as well as to control sea lines of communication. Corbett emphasized that these actions best suited an island nation like Britain XXX. He strove to place naval strategy within a larger framework of a maritime strategy working in conjunction with ground forces in support of limited war to protect national interests. Corbett’s focus on limited war was important because it emphasized using limited forces to maximum advantage in order to protect the nation’s economic livelihood. He realized that this was crucial for an island nation like Britain needed to use multiple instruments of

mistaken identities and misunderstanding within twelfth night

‘Comedy relies on familiar sources of misunderstanding’. To what extent are mistaken identities and misunderstanding central to the comedy of ‘Twelfth Night’? Much of the Shakespeare’s ‘Twelfth Night’ focuses on misconceptions and the way disguises cause the root of misunderstandings in which mistaken identities arise, a fortuitous device for complicating action. Critic John Hollander described the play to be a ‘ritualized Twelfth Night festivity in itself’ . The comedic aspect is all due to the privileged position that the audience hold, consuming more understanding of the true situation than the characters themselves. It also manages to expose the habits and pretences people in the modern world take for granted, thus linking to†¦show more content†¦Cesario soliloquizes and rhetorically questions ‘I left no ring with her; what means this lady?’. By inserting a caesura the effect of it portrays and emphasises ‘his’ change in tone, juxtaposing with the image portrayed of a romantic relationship, the passage also being formed of a natural and conversational style. Notably, the gift of the ring shows similarity to the commemoration of the coming of the Three Magi bearing gifts. Epiphany, a Christian feast held on Jan 6th, blessed the revelation of God the Son as a human being . Significantly, gender identity and deceptions cause the romantic complications that are presented. There is a plot parallel between Shakespeare’s play and the Italian ‘Gl’Ingannati’, dated 1531, as the main theme for both is the mistaken identity largely prevalent. Folly and bawdy humour are generated from the sub characters. With Sebastian introduced, the issues of mistaken identity end culminating in sudden marriage. Similarly, Fabrizio returns and everything is rushed in his infatuated based relationship and engagement with Isabella. Through the visual human pun of twins used by Shakespeare in both ‘Twelfth Night’ and ‘Menaechmi’, alongside the Italian ‘Gl’Ingannati’, the siblings manage to tap into an innately human fascination. Shakespeare incorporates a feminine twist to the action presented from Act 3 Scene 1, later generating Helmuth Plessner’s belief that comedy comes from desensitization of a character. ThisShow MoreRelatedThe Limitations Of Frye s Green World 1729 Words   |  7 PagesWhat are the limitations of Frye’s ‘Green World’ model as applied to ‘Twelfth Night’ by William Shakespeare? Twelfth Night was thought to be written in 1600-1. The play – known for adhering to a genre of romantic comedy by utilising pathos combined with humour – is listed under comedies in the First Folio of 1623 with another of Shakespeare’s works As You Like It. Twelfth Night adheres to Frye’s theory to some extent. The old world, one of repression, is conveyed through the puritanical beliefs ofRead MoreTwelfth Night by William Shakespeare Essay1100 Words   |  5 PagesTwelfth Night by William Shakespeare First impressions of Twelfth Night can be deceiving as on a simplistic level it can be portrayed as a typical Shakespearean comedy. However, Twelfth Night is a mixture of both romantic comedy and tragedy. The romantic comedy elements can be found throughout the play as its structure is based on a typical Elizabethan style, it has escapism with magical settings and happy endings, as is Midsummers Night Dream. Also Twelfth nightRead MoreMarriage and Twelfth Night1541 Words   |  7 Pages‘At the end of Shakespeare’s comedic plays all complications and disorders are resolved and a new order is generated to the satisfaction of the audience.’ to what extent is this true of Shakespeare’s Twelfth Night? It is easily argued that Shakespeare’s comedic plays have a similar, formulaic, structure. 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Lycan The theory or doctrine of mind-brain identity, as its name implies, denies the claim of dualists that mind and brain (or consciousness and matter)Read MoreWilliam Shakespeares As You Like It As a Study of Perception and Misperception2315 Words   |  10 Pagesare common themes in many of Shakespeares plays and can be found in his comedies, tragedies and histories alike. Shakespeare explores these often-parallel elements through several different forms in his work, such as disguise, mistaken identity and blindness, and events caused by these can lead to amusing, confusing or sometimes tragic consequences, depending on the nature of the plays themselves. The Concise Oxford Dictionary defines perception as the ability to Read MoreLogical Reasoning189930 Words   |  760 Pagesyouve been having a good time. Yesterday you drove several hours into the area and parked in the main parking lot. Then you hiked six hours to your present campsite. The three of you carried all your food, water, sleeping bags, and tents. Last night you discovered that somebody had accidentally cracked the large water container. Now you are stuck with no water. Although there is a stream nearby, you wouldn’t normally drink from a stream, and you remember that your packets of water-sterilization

In Jesus’ Name Taking Up Serpents Free Essays

â€Å"Happy shall he be, that taketh and dasheth thy little ones against the stones. † (Psalm 137:9)Read more at /list/top-20-bible-passages-to-use-against-fundamentalists/ivana-wynn? page=3#X63UZMIZkY7ETEaQ. 99 â€Å"Happy shall he be, that taketh and dasheth thy little ones against the stones. We will write a custom essay sample on In Jesus’ Name: Taking Up Serpents or any similar topic only for you Order Now † (Psalm 137:9)Read more at /list/top-20-bible-passages-to-use-against-fundamentalists/ivana-wynn? page=3#X63UZMIZkY7ETEaQ. 99 Megan Gowler Cultural Anthropology MWF 10 a. m. IN JESUS’ NAME: TAKING UP SERPENTS I’ve took cocaine, I’ve smoked marijuana, drunk whiskey, and been high on all that, but this high you get on Jesus, it’s nothin’, nothin’ compared to that†¦ † The video was filmed in two churches in Alabama and Georgia in what looks like the 60’s, but in reality was the late 80’s or very early 90’s, I believe the copyright date is 1991. In Jesus’ Name: Taking Up Serpents heavily documents the practice of snake handling in this religious sect, but mentions the consumption of strychnine very minimally. The people seem happy, but not particularly affluent. They are presumably in the Appalachian region of the states, where coal mining, poverty and a hard life are all too common. The whole thing is presented without commentary or criticism allowing the viewer to experience the culture and apply their own opinions. Taking Up Serpents shows us how literal interpretations of biblical texts are executed with fervor in the name of God. The filmmakers do not appear biased or like they have any hidden agenda. It seems to be a straight-forward documentation of a church service. The filmmakers did not go out of their way to make these people seem simple or poor, which I am sure would have been easy to do with selective editing. Men are featured prominently in this video. They seem to be ‘called upon by the holy ghost’ to ‘take up serpents’ more readily than the women are. The women are not left untouched by the ‘spirit’ as was made obvious by the shaking, sobbing and speaking in tongues that is also demonstrated in the video. The women who do handle the snakes seemed to do so for a much shorter length of time and with greater caution then the men, who shake them and rub them around their faces and necks, almost as a challenge to the snake. Children are not permitted to handle any of the snakes in these churches. I found out online that usually (and for legal reasons) you must be 18 to begin taking part in this part of the ritual. Apparently, the Holy Spirit discriminates by not just gender, but age as well. They do not go into any detail regarding the consumption of strychnine in this video, it only gets a brief mention and is hardly shown. Interestingly, when you look at the side effects of the consumption of strychnine, one of the less grievous effects is euphoria. Also, it should be noted that it acts as a stimulant and can cause muscle spasms and convulsions, which are exacerbated by bright light and loud noises (I assume that includes raucous religious music and bright overhead lights). I wonder why they have chosen that verse specifically to focus all their energy on. Why aren’t they burning male flock animals (sheep, goats) on altars in their yard or beating their children for self satisfaction (Leviticus 1:9 and Psalm 137:9, respectively). Why snake handling and poison consumption, I have a theory, but I will save it for now. Everything about this practice is bizarre, but is it only bizarre because of our distance from it? Religious ceremonies of EVERY nature have incredibly odd practices, but they only seem bizarre to outsiders. The whole video made me sad, but I can’t say exactly why. The filmmakers intention was to document the practice and according to the note on Youtube, help preserve their right to practice their religion, their way. I don’t know how to explain how I feel without writing another 5 pages. Religion and religious freedom is and always has been a minefield of controversy. Islam has the prophet Mohammed who took a six year old bride when he was in his late 50’s, Christianity has a virgin birth and coming back to life (insert inappropriate zombie Jesus joke here), Scientology teaches us that we are all immortal aliens trapped in physical bodies, dinosaurs are a hoax put forth by Satan to fool us all, Mormons are in their ‘magic underwear’ prepping for the return on God in Missouri, putting a dirty milk glass and a plate from a roast beef sandwich in the same dishwasher can contaminate your soul, or most famously and least disputed the idea that when certain rites are performed bread and wine turn into human flesh and blood once in your stomach. I mean, there are plenty of genuinely weird ideas and practices in the United States, I mean, these are just off the top of my head. So even though this very specific sect of Evangelical Christians has the odd little habit of swinging snakes around and drinking poison really, who can judge the m? I would like to mention that I did a little digging regarding this film, partly because I am fascinated by religion and partly because I wanted to know more about it and I found out that two of the men in the film have died, possibly a third, but without names, I cannot say for sure. Also, the pastor in the film, whose name is Glenn Summerford was convicted of attempted murder for stuffing his wife Danielle’s hand into a box of rattlesnakes when he was in a ‘drunken rage’ in 1991. Glenn was sentenced to 99 years in prison. There is a book about this titled, The Serpent and the Spirit and I now intend to read it as well. After some of the additional information I have uncovered and a lot of the stereotypes we have all heard regarding people living in this area, I wonder if these people live their lives in a more rowdy fashion than you would imagine given the scenes we are shown in the film, which is why I placed the quote I did under the title at the top. The skeptic cynic in me says that the snake handling has less to do with God or the Holy Spirit and more to do with each individual using this fate tempting to make themselves feel better, maybe about indiscretions, financial hardships, poor decisions, who knows? Do something wrong, feel guilt, handle the snake, live through it, decide God isn’t that mad at you after all because he is a forgiving God and you made a mistake, feel better†¦ now repeat. I suppose that is what every religion is supposed to do for its followers, make you feel better, help you find peace, give you a sense of place, let you know that ‘it’ is gonna be okay. So as a non-judgmental observer with no plans of attending service or joining the Church of Jesus with Signs I say, ladies and gentlemen, turn up your amps, raise your cups of strychnine and shake those snakes! How to cite In Jesus’ Name: Taking Up Serpents, Papers

Strategic Marketing Management Customers at Work

Question: Describe about the Strategic Marketing Management for the Customers at Work Circumstances? Answer: Changing microenvironment factors that impact on Ford Microenvironmental factors Microenvironmental factors are depending on various active stakeholders of a company. These stakeholders have their great effect on the business. To execute the environmental factors on the organizations, Ford has been chosen for this study (Dunkel Kleemann, 2013). The effects of microenvironmental factors are having a great impact on the marketing of the Ford. The factors are described as follow: Customers: Ford has an excellent customer base all over the world. They also give customer benefits and adaptable service for the customers. Depending on the market the Ford is gaining more customer support from different countries (Dunkel Kleemann, 2013). Suppliers: The suppliers are very superior in the Ford. The vendors are providing the best products at a low price as the market is becoming very much competitive. So, this is becoming a great impact on the organization. Distributors: distributors are promoting the cars for the organization and also making the product knowledgeably to the customers. The Ford has many sellers who promote and sell the products directly to the public (Shankar Carpenter, 2012). Competitors: The competition level of the automobile industry is very much impressive. He BMW, Volkswagen, Benz, and Hyundai are the main competitors of the organization. the competition level is as follow: SWOT analysis Strength Weakness 1. Increasing customer base 2. International growth 3. Increasing market share 1. Low price focus 2. Previous debts 3. Mainly depends on UK clients. Opportunity Threats 1. More international acceptance 2. New car launch 3. New formats 1. Increasing competitors range 2. Loosing upper level customers 3. New competitors in the market References Dunkel, W., Kleemann, F. (2013). Customers at work. Houndmills, Basingstoke, Hampshire: Palgrave Macmillan. Shankar, V., Carpenter, G. (2012). Handbook of Marketing Strategy. Cheltenham: Edward Elgar Pub.

Smart Home Heating Control Panel

Question: Describe about the Smart Home Heating Control Panel. Answer: The Smart Home Heating Control Panel was aimed at designing a user interface that could easily take up the functions that are currently provided by a control panel mounted on the walls. The primary objective of this project was to design the user interface to be used for controlling the thermostat in accordance to the principle guidelines of interface designing, to develop the said designs using software tools, to evaluate the according to various usability evaluation techniques and to finalize the designs. Needless to say, any changes to the hardware components of the thermostat or that of the control panel were way out of the scope of the project. Before the designing process began, a session was conducted for collecting information regarding the various operations that the sad thermostat is capable of. The information provided by the manufacturers indicated that the thermostat currently supports three modes of heating: heating by hot water, heating by hot air, heating by steam and heating by electricity. All of the said modes can again be utilized to set up certain temperature zones': these specialized settings comes to use when the user does not want to change the heating mode or temperature of the room each time the thermostat is put on. The manufacturers of the said thermostat also conveyed to us the fact that they want to provide their users with certain unique functionalities: the higher management of the manufacturing organization had envisioned the design of the user interface to be capable of supporting functionalities which would allow the customers to preheat the rooms. These discussions lead us to believe that the following are the business requirements of the said project: i. Manual temperature control: The interface being designed should allow the users to change the temperature settings of the thermostat, so as to control the temperature of the room, in a manual mode. ii. Quick temperature control: The interface being designed should allow the users to change the temperature settings of the thermostat, so as to control the temperature of the room, using the quick temperature settings. iii. Personalized temperature control: The users should be capable of using various customized settings functionalities to control the room temperature. iv. Automated temperature control: The automated temperature mode of the thermostat should also be supported by the user interface. v. Turn off / Turn on / Reset: The user interface should provide the users options for turning on the thermostat, turning it off when not required and resetting it. vi. User Interaction: The user interface being designed should allow human interactions. vii. Display: The graphical user interface should essentially display the various functionalities available for controlling the thermostat. viii. Ease of Use: The user interface being designed should be easy to use. Once the business requirements of the manufacturers were identified, we started designing the user interface: the following components were included in the design so as to meet the above mentioned requirements. Sl. No Business requirements Design component included i Manual temperature control: The user interface contains in built features for supporting Manual temperature control Ii Quick temperature control: The user interface contains in built features for supporting Quick temperature control iii Personalized temperature control: The user interface contains in built features for supporting Personalized temperature control Iv Automated temperature control: The user interface contains in built features for supporting Automated temperature control V Turn off / Turn on / Reset: In built features for turning on/ turning off and resetting the thermostat has been included in the user interface vi User Interaction: The entire interface has been designed so as to be operated by human touch. Vii Display: The user interface essentially displays the functionalities available for temperature control viii Ease of Use: The user interface has been designed keeping in mind the ease of use of the customers. It is worth mentioning that while developing the design of the user interface, the project team were cautious about the fact that the designs need to be in accordance with the Eight Golden Rules of Interface Design," as proposed by Ben Schneiderman (Schneiderman, 1986). Hence, the entire interface has been split up into several pages, besides including functionalities for redoing any action that has once been performed by the user. Last but not the least, we would like to accept the fact that our designs have been significantly influenced by several smart phone applications that are readily available in the market: however, we have only been inspiring by such designs and have not copied' any component is our interface design. Bibliography Gremeau, L. (2012). Service Providers the Smart Home (1st ed.). Nielsen, J. (2012).Thinking Aloud: The #1 Usability Tool.Nngroup.com. Sachs, O., Duvier, C., Cheney, K., Akers, C. (2012). Schneiderman, B. (1986). Eight golden rules of interface design.Disponible en. Tsopra, R., Jais, J. P., Venot, A., Duclos, C. (2014). Comparison of two kinds of interface, based on guided navigation or usability principles, for improving the adoption of computerized decision support systems: application to the prescription of antibiotics. Journal of the American Medical Informatics Association, 21(e1), e107-e116. Tuch, A. N., Roth, S. P., HornbK, K., Opwis, K., Bargas-Avila, J. A. (2012). Is beautiful really usable? Toward understanding the relation between usability, aesthetics, and affect in HCI. Computers in Human Behavior, 28(5), 1596-1607.

What can we learn about human nature from our relatives, the chimpanzees

Introduction Human beings represent the most evolved primates and their brains are the most developed among the mammals of the order Primate. Through millenniums of evolution, human beings have developed complex cultures and behavioral traits that characterize humans. However, primatologists have suggested that characteristics of human nature might not be limited to humans and primates such as the chimpanzee might share some of these features.Advertising We will write a custom research paper sample on What can we learn about human nature from our relatives, the chimpanzees? specifically for you for only $16.05 $11/page Learn More Chimpanzees are unique among the primate group since they are man’s closest living relatives. Anthropologists believe that by studying these primates, we can gain insight into human behavior. Renowned primatologists such as Frans de Waal declare that the behavior of chimpanzees can provide important clues about human natu re. With this in mind, this paper will engage in an in-depth analysis of what we can learn about human nature from our relatives, the chimpanzees. Lessons from Chimpanzees Social Life Human social life can be informed by studying the chimpanzees. Specifically, chimpanzees demonstrate that primates thrive better in a communal setting than they do in isolation. Chimpanzees normally live in colonies, which are made up of males, females, and the young ones. While all the members of the colony engage in activities such as foraging and hunting, to sustain themselves, the group stays together as a community. The importance of social interactions in promoting peace is highlighted by studying chimpanzees. When groups of chimpanzees exist live together, they engage in activity such as mutual grooming, which reinforces the relationships between them. Because of this reinforced relationship, a social bond is created among the members of the group. The bond helps to promote peace and foster re conciliation when conflicts arise. In the same way, human beings are likely to coexist peacefully if they engage in activities that foster social bonds. People who engage in communal activities that strengthen social bonds are unlikely to act aggressively against each other. Self-interest is natural and it helps in the creation of behavior that is beneficial for all. In chimpanzee communities, many animals live together and act in a cooperative manner to ensure their survival. Due to self-interest, individuals avoid engaging in behavior that would lead to the collapse of the troop. The young ones in the groups are taken care of by their mothers and the rest of the group. Kupperman contends that the self-interest of human beings led to the formation of agreements that create constraints on various forms of harmful behavior (101). People therefore act in a cooperative manner out of self-interest.Advertising Looking for research paper on philosophy? Let's see if we can help you! G et your first paper with 15% OFF Learn More The ability of human beings to adapt themselves to their environment can be learnt from chimpanzees. The main distinguishing factor of human beings from other primates is their ability to adapt to their environment and use tools to increase efficiency. This ability is not confined to humans and chimpanzees demonstrate their adaptively in the wild. Chimpanzees have been observed to use stone tools to crack hard nuts and sticks to assist in the gathering of food. While this actions are very primitive compared to the ability that human beings possess, they demonstrate that it is in human nature to adapt to the environment. Social Order Studies on chimpanzees explain the sense of property observed in humans. Of all the primates, human beings have the most complex system of ownership and succession with laws being in place to protect ownership. People have an intuitive understanding of â€Å"mine† and â€Å"your† and a series of social norms and governance structures are in place to manage the relationship that exists because of property. However, this sense of property is not restricted to humans and other primates have at least elements of ownership (Brosnan 10). When chimpanzees encounter food that is held by another member, they show the behavior of begging or sharing of food instead of taking it by force, therefore suggesting that these primates understand the concept of ownership. The chimpanzees show respect for objects possessed by others and they do not try to take these objects even if the possessor is smaller and unable to defend his property through force. This suggests that â€Å"respect for possession† is not a product of human culture and civilization but rather a product of nature. Chimpanzees offer insight on the ways through which humans control each other’s behavior in the community. These primates demonstrate that ostracizing, as a way of encouraging conformity in order to increase social cohesion, is a natural concept. Ostracism, which is the practice of rejecting or excluding certain individuals, is deeply embedded in human society. However, this practice is discouraged in modern society since it can undermine the legal system in place and promote rejection of minority groups such as gays and lesbians. However, studies on chimpanzees show that ostracism is natural and bears positive outcomes. In chimpanzee communities, social order is maintained by the habit of shunning and isolating individuals who act in a defiant manner.Advertising We will write a custom research paper sample on What can we learn about human nature from our relatives, the chimpanzees? specifically for you for only $16.05 $11/page Learn More Ostracizing therefore plays an integral role in ensuring that the group cohesion is maintained and conforming behavior is encouraged among the members. Human beings also practice ostracism as a form of p unishment for non-conforming or deviant behavior of individuals in society. Studies on the behavior of chimpanzees show that using ostracizing is an effective method of maintaining social order. Ostracizing helps to encourage conformity to group norms and therefore foster good relationships among individuals. Culture Development of culture has been assumed to be a strictly human function. However, primatologists demonstrate that culture exists in chimpanzee colonies. Chimpanzees that come from different geographical locations exhibit varying cultures. As such, these primates display multiple cultural traits in the same way that human beings do. From this, we can learn that human culture is a product of nature. This should lead to an appreciation of the fact that different communities exhibit different languages, eating habits, traditions, dressing, and so on. We can gain an understanding about the human learning process by observing how chimpanzees learn from each other and pass d own behavior from the older to the younger generations. Older members of the colony show young ones how to behave and teach new skills on them. This active teaching increases the chances of survival for the chimpanzees as the knowledge necessary for survival is acquired and used by the young ones. Learning and cognition is therefore natural for primates including human beings. From studying chimpanzees, it is evident that human beings are naturally inclined to learn from others and pass down information and knowledge from one generation to the next. Insight into communicative patterns by human beings can be gained from observing chimpanzees. Specifically, clues about nonverbal communication can be seen from these primates. Communication is an integral part of human life and communication has played a major role in the advancement of human civilization. In addition to the verbal communication, humans make use of gestures many non-verbal cues. Frans de Waal suggests that nonverbal com munication is a natural form of communication since gestures are used by most primates (22).Advertising Looking for research paper on philosophy? Let's see if we can help you! Get your first paper with 15% OFF Learn More War and Aggression It has long been assumed that violence is an inherent part of human nature. This assumption has been reinforced by the many instances of war and aggression carried out by human beings for centuries. Research on chimpanzees indicates that violence might be an innate attribute of primates. Groups of chimpanzees engage in aggressive behavior and violence against outsiders and sometimes against members of their own colony. However, these primates tend to avoid aggression and instead coexist peacefully if they can. This behavior is similar to that of humans who are prone to acts of aggression against others. In addition to this, chimpanzees form coalitions in order to strengthen their attacks. Chimpanzees are likely to engage in coalitional aggression where a number of chimpanzees gang up to attack a common enemy. This strategy is preferred since it results in a high likelihood of winning while minimizing the costs of aggression to the individual. Human beings are al so in the habit of forming coalitions with each other in order to strengthen their attack. Another lesson on aggression from chimpanzees is that it is mostly confined to males. Frans de Waal observes that males were likely to gang up against out-group males and initiate attacks against them (80). Male aggressions are also more likely to escalate into deadly attacks. On the other hand, females are unlikely to engage in coalitional aggression and their conflicts rarely escalate to deadly levels. This is similar to human beings where men are more aggressive and play a bigger role in the proliferation of war compared to women. Sexuality Some issues of human sexuality can be learnt from observing chimpanzees. Human beings regard incest as a taboo and all societies refrain from this practice. However, there are doubts as to whether this taboo is a purely cultural product or a product of nature. The study of chimpanzees suggests that the incest taboo is a law of nature that has permeated all cultures. Primatologists document that chimpanzees avoid incest on their own accord and young females are strongly attracted to unfamiliar males whom they seek outside their own community (Frans de Waal 22). Some lessons on human behavior concerning sex can be learnt from chimpanzees. While chimpanzees are not monogamous, their sex life is not completely promiscuous. Frans de Waal states that the sexual intercourse among chimpanzees is subject to clearly defined rules (22). In some cases, males are keen to demonstrate their sexual dominance and protect their sexual partners. The dominant male will chase away the other males in the colony who try to mate with his females. This can be compared to the family unity where the male guards all sexual rights and privileges in the institute. Conclusion Chimpanzees are commonly used for comparison with humans to understand some issues on human nature. This paper has engaged in a discussion of the lessons on human nature that can be learn t from chimpanzees. It has demonstrated that there are great similarities between the social life of humans and chimpanzees. Both perform better in communal settings and individuals cooperate with each other for mutual interest. Concepts such as respect for property and social cohesion are common in both primates. The paper has shown that violence is a part of human nature and males are the greater aggressors. The common sexual conducts have also been highlighted. Through this exploration of chimpanzee nature, the natural basis of some human behavior can be recognized. Works Cited Brosnan, Sarah. â€Å"Property in nonhuman primates†. Origins of ownership of property. New Directions for Child and Adolescent Development 132.1 (2011): 9–22. Web. Frans de Waal, Frans. Chimpanzee Politics: Power and Sex among Apes. NY: JHU Press, 2007. Print. Kupperman, Joel. Theories of Human Nature. Boston: Hackett Publishing, 2010. Print. This research paper on What can we learn about human nature from our relatives, the chimpanzees? was written and submitted by user BartRozum to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Leprechaun Trap - Green Slime St. Patricks Day Project

Leprechaun Trap - Green Slime St. Patricks Day Project Heres how to make green slime for St. Patricks Day leprechaun trap. We havent successfully caught any leprechauns using this recipe yet, but it does make a nice holiday chemistry project for kids! Leprechaun Trap Slime Materials 4-oz bottle school glue gelborax (not boric acid)watergreen food coloring Make the Leprechaun Trap Slime Solutions The leprechaun trap is made by mixing two solutions together, which cross-link or polymerize to make a gel or slime. First, make the solutions: Borax Solution Take about a half cup of hot water and stir in borax until it stops dissolving. It is fine if the solution is cloudy or if there is undissolved solid at the bottom of the container. Just add the liquid part to your slime recipe. Glue Solution You can make either opaque slime or translucent slime, depending on the type of glue you use for this project. White glue produces an opaque slime. Clear or translucent blue glue will produce a translucent slime. You can color either type of slime using food coloring. Stir 4-oz of glue into 1 cup of water.Add a couple of drops of food coloring. The radioactive chemistry green-yellow color is obtained by adding 2 drops of yellow or 2 drops yellow and 1 drop of green coloring, depending how green you want the slime. For a leprechaun trap, you can add a few drops of green food coloring and call it good. If youre a rebel, dye the slime blue! Blue was the traditional Irish color before green came into vogue. Make the Leprechaun Trap Simply mix together 1/3 cup of the borax solution and 1 cup of the glue solution. You can use your hands or you can use a spoon. Glowing Leprechaun Trap What leprechaun wouldnt be attracted to a glowing trap? You can make the slime glow very brightly under ultraviolet or light if you add a little yellow highlighter ink to either of the solutions. Highlighter ink is fluorescent, so it emits light when exposed to high-energy light. Note adding the contents of a glow stick will not work, because the other chemicals in the slime will interfere with the reaction that produces the glow. Cleaning Up the Leprechaun Trap Although regular slime doesnt stain most surface, the food coloring you added to make it green will stain clothing, furniture, and counters. You can remove the color from countertops using cleaner with bleach. Except for the food coloring, slime washes away with soap and water or in regular laundry. After St. Patricks Day Your leprechaun trap wont last until St. Patricks Day next year, but if you seal it in a covered bowl or a plastic bag, it will be good for several days. You can extend this to a couple of weeks if you store the bag in the refrigerator. The sealed bag keeps the slime from drying out while the refrigerator keeps it from developing mold. How Leprechaun Trap Slime Works When you mix the glue and the borax the polymer in the glue, polyvinyl acetate, undergoes a chemical reaction. Cross-linking bonds are formed, causing the glue stick less to your hands or spoon and more to itself. Feel free to experiment with the amount of glue, water, and borax that you use to make the slime. You can adjust the recipe to make the slime more fluid or more stiff. The molecules in the polymer are not fixed in place, so you can stretch the slime quite far before it will break or tear. More St. Patricks Day Science Projects Turn Pennies Gold for a Pot of GoldGreen St. Patricks Day FireGlowing Green FlowersMore St. Pattys Day ProjectsAnswers To Common Questions About Slime

Insider threart Essay Example | Topics and Well Written Essays - 250 words

Insider threart - Essay Example Insider threat has been classified to include fraud, espionage, theft of intellectual property and IT sabotage. These normally cost an organization a heavy loss and most of them barely ever recover. There are several actions that an organization can take in order to prevent its vulnerability to internal threats. First, the organization can take the initiative to educate the employees and make them fully aware of what comprises an insider threat. Employees need to understand that they also need to work in the best interest of the organization and report any suspicious or malicious activity that may be taking place in the organization (Finan, 2013). Secondly, the management can implement strict password and management policies and practices to ensure the security of the organization by limiting employee’s access to any confidential information. In addition, the organization should have a secure recovery and backup processes in place in order to ensure they can easily handle the threat without letting it get out of hand. In conclusion, no company should imagine that they are completely safe from insider threat. It is important that they take the essential steps which are applicable to their organization in order to ensure some form of security. Most companies find it hard to recover because most insider threats are skilled professionals and the companies are rarely ever prepared for it (Finan, 2013). Finan, E. (2013). A Preliminary Examination of Insider Threat Programs in the U.S Private Sector. Intelligence and National Security Alliance. Retrieved From :

Science Fiction, Technology, and Our Modern World Essay - 2

Science Fiction, Technology, and Our Modern World - Essay Example The brain in a vat scenario depicts a situation where all beliefs we hold about the world would presumably be false despite the fact that they are justified. Brain in a vat argument presents a situation where a removed human brain placed in a life-sustaining fluid and connected to computers that provide exactly the same impulses as the body. The computers effectively create a virtual reality. The person with the disembodied brain continues to have a perfect life without a relationship with the object of the real world. The person will not be able to discover the reality of their simulated world thus transferring my consciousness to a computer would make no difference, I will not mind. Q2. Metaphysics is concerned with the fundamental nature of reality whose hypothesis may claim the truth underlying physics. It may also say a thing about our mind’s nature or creation of the world. Matrix hypothesis is regarded as a metaphysical proposition with all the three elements. These are the reality underlying physics, nature of our minds and the creation of the world. Each of these elements is coherent, and cannot be ruled out conclusively and none of them is a skeptical hypothesis. Matrix and metaphysical hypotheses are similar in three-part version. The fundamental computation of the physical processes, the separation of our cognitive systems from physical processes while interacting with these processes and lastly the physical reality created outside the physical space. One may make various objections. For instance, one might argue that the matrix hypothesis implies a computer simulation where physical process exists but not simply that the physical processes themselves exist. Matrix hypothesis seeks to create consciousness in minds, which may or may not be fully aware that they are living in a simulation. Q3. Computer games and simulations are interactive multimedia whose

Treatment Research for Multiple Myeloma (MM)

Treatment Research for Multiple Myeloma (MM) ABSTRACT INTRODUCTION Multiple myeloma (MM) is a hematological neoplasm that appears after transformation and uncontrolled proliferation of plasma cells. MM is characterized by a heterogeneous genetic aberrations and very different clinical outcomes (Avet-Loiseau, . Boyd KD). Although treatments for MM have increased by develop new and more sophisticated therapeutics drugs such an immunomodulatory drugs (IMiDs) and proteasome inhibitors (PIs)( Shaji K. Kumar, Raghupathy, Antonio Palumbo) the marked variability of responses indicate that larger studies will be required. Currently, identification of cytogenetic abnormalities is performed by conventional karyotyping and fluorescence in situ hybridization. However, these disorders are not sufficient to explain the malignant phenotype given that are also observed in premalignant states of MM such a monoclonal gammopathy of unknown significance (MGUS) or smoldering myeloma(SM)(Bergsagel, Hideshima). This finding justifies the need for a comprehensive screening of genetic abnormalities in MM patients, which has not been incorporated in the medical workup yet. Recently, the introduction of massive sequencing of patient genome using next-generation sequencing (NGS) technologies has considerably increased the understanding of the biological features of MM. Many works have described the complex and heterogeneous mutational profile of MM patients(bolli nuevo, walker). Whole Exome Sequency (WES) studies in newly diagnosis MM patients have confirmed that more than 50 genes are mutated in the first manifestation of disease (walker). However, only few genes have been detected recurrently mutated at diagnosis, including KRAS, NRAS, BRAF, DIS3, TP53 and FAM46C, and only TP53 mutations have been recurentelly associated with poor survival. In addition, other studies have assessed the clonal evolution over time, pointing out that systemic treatment with chemotherapy may affect the livelihood of some subclones more than others, and thus may influence the tumor evolution over time(Egan JB, bolli, Keats JJ, ) The introduction of targeted studies allows the detection of mutations even with very low allele frequencies at an affordable price, allowing the incorporation of extensive genetic studies to the clinical workup. In the last years, several groups have applied this approach in order to achieve a better patients stratification and prognosis prediction. Although many studies have highlighted the importance of the subclonal landscape in MM and many efforts have been undertaken to stratify patients and predicts their responses, there is no clear relation between sensitives or refractories clones to treatment, and more information about the prognostic impact of this subclonal profile in series of homogeneously treated MM patients is needed. A large number of clinical trial are being carried out with this aim, unify treatments in order to study more effectively the impact of genetic alterations in prognosis. In this work, newly diagnosis MM patient homogenously treated have been genetically characterized using a combination of the most recent techniques, including FISH and ultra-deep targeted sequencing. We applied the highest read depth described in the literature with the aim to detect minority subclones ignored to date. We also integrated these data with the clinical features to find out new patterns of behavior, relate them with survival and reveal new insight into the complexity of clonal and subclonal architecture of MM. Patient samples Samples were taken from the available 79 newly diagnosed MM patient enrolled in the clinical trial GEM10MAS65 (registered at www.clinicaltrials.gov as #NCT01237249). This is a phase III trial where patients older than 65 years were randomly assigned between two treatments arms: sequential melphalan/prednisone/Velcade (MPV) followed by Revlimid/low dose dexamethasone (Rd) versus alternating melphalan/prednisone/Velcade (MPV) with Revlimid/low dose dexamethasone (Rd). Progression free survival (PFS) and overall survival (OS) were measured from the starting date of the treatment. The median time to progression was 26.4 months with a median follow up of 31.5 months. Targeted sequencing and mutation calling Positive plasma cells CD138 were isolated from bone marrow aspirates and DNA was extracted using AllPrep DNA/RNA mini kit (Quiagen). Only 20 ng of DNA were used to prepare libraries using Ampliseq Library Kit 2.0. We also sequenced DNA from the 15 available CD138 negative fractions in order to filter out potential artifacts and corroborate detection sentivity. Samples were sequenced using Ion Torrent platform (IonProton, Thermofisher, Carlsbad, CA, USA) using the M3P gene panel (Mayo Clinic, Arizona). This panel spreads out over 77 genes frequently mutated in MM, which are related to critical pathophysiological pathways, associated to drug resistance or targetable with molecular drugs [paper mayo kortum etal]. Quality filter and alignments was performed using Torrent Suit software (Life Technologies) Single nucleotide variants were calling and annotated using Ion Reporter software applying in-house modifications in call variants process. Variants listed in Single Nucleotide Polimorph ism database (dbSNP, http://www.ncbi.nlm.nih.gov/SNP/) were excluded from samples without germline available, as well as variants that were detected in multiple samples. In addition, to test the ability of the workflow previously described, we applied a novel bioinformatics pipeline developed by Spanish National Cancer Research Centre (CNIO). All reported mutations were detected by both bioinformatics approaches. The integrative genomic viewer (IGV) was used to visualize the read alignments, single variants and correct sequencing errors due to homopolymer regions. Statistical analysis All statistical analysis was performed using the statistical environment R. Correlation coefficients between mutated genes and cytogenetic aberrations was assessed and plotted using corrplot (https://cran.r-project.org/web/packages/corrplot/). Differences in survival were tested using the log-rank test. Cox proportional hazard regression was employed to obtain hazards ratios (HR) and evaluated at 5% of significance level. A second approach called LASSO (least absolute shrinkage and selection operator) was performed to detect relevant variables among clinical, cytogenetic and mutated genes.   Further details can be found in Data Supplement. RESULTS Mutated genes and altered pathways (cambiar tà ­tulo) We sequenced 79 tumor samples with a mean coverage depth of 1600X. The minimum coverage of the detected variants was 60X and the average coverage 370X. We identified 170 nonsynonymous missense/nonsense/stoploss single variants, 81 of them (48%) were predicted pathogenic by Sift and Polyphen and 61 (36%)   have been described in COSMIC data base.   85% of patients harbored at least 1 mutation with a median of 2.1 mutations per patient. We detected mutations in 53 genes (Figure1), although 6 genes accounted the 39% of the total number of mutations; KRAS= 21.5%, DIS3= 19%, NRAS= 16.5%, BRAF= 10.1%, TP53= 8.8% and ATM= 7.6% of the patients.  Ã‚   48% of patients (38/79) presented at least one mutation in genes envolved in RAS/MAPK pathway, being the most frequently mutated pathway. 72 and 100% of variants in KRAS and NRAS respectively were detected in the hotspot codons 12, 13 and 61, and the targetable V600E BRAF mutation was detected in 1 patient. (Figure 2 supplemental?). NFKB p athway was the second most frequently mutated in our cohort, accounting for the 15% of all mutations distributed in 25 % of the patients (19/79). This pathway included TRAF3 (5 mutations, one nonsense and 4 missense) and TRAF2 (3 missense mutation) all of them predicted pathogenic by Sift and Polyphen. Other pathways importantly altered in the cohort were MYC in 11% of patients (9/79), cereblon and ciclyn both in 9% of patients (7/79). Multiple mutations within the same gene were observed in 11 patients: 4 of whom harbored 2 and 3 mutations within DIS3 (patient 1-24= Glu501Lys and Phe120Leu at 8 and 53 % of VRF, patient 2-236= Asp487His and Asp479Glu at 4 and 21 of VRF respectively, patient 3 321= Tyr753Asn and Glu126Lys at 2 and 58 % of VRF respectively and patient 4-42 = Arg820Trp, Gly249Glu and at 14, 20 and 24% of VRF respectively). Other 2 patients showed 2 and 3 mutation in KRAS (patient 5-168= Gly13Asp and Gln61His at 9 and 13 %of VRF and patient 6-269 = Tyr71Asp, UTR3 in exon 6 and Gln61Glu at 3, 15 and 37 % of VRF respectively; 2 patients with 2 mutation in NRAS(patient 7-177= .Gln61Lys   and Gly12Ala at 5 and 12% of VRF respectively and patient 8-257=   Gln61Glu   and Gly12Ala at 5 and 6% of VRF respectively), one patient with 3 mutations in MAX (patient 9-190= Arg36Lys , Arg35Leu and Glu32Val at 10, 20 and 26 %of VRF), one patient with 3 mutations in TRAF3 (patient 10-40 = Lys453Asn, His136Tyr   and Phe445Leu 8, 11 and1 3% of VRF) and one patient with 2 mutation in TP53 (patient 11-40 = Asp208Val   and Glu204Ter at 35 and 36% of VRF respectively). Variant Read Frequency study The VRF found in our cohort were diverse.   We detected 50% of variants (85/170) below 25% of VRF and 27% (46/170) below 10% (Figure 2). KRAS (n=5) DIS3 (n=5), BRAF (n=4), NRAS (n=4), and TP53 (n=3) were the genes that harbored the largest number of low frequency mutations (Figure 2). KRAS, NRAS, BRAF and TP53 mutations were, in all cases, lower than 50% of VRF while DIS3 showed mutations in a broad range (from 2 to 85%)(Fig3). ). Most of DIS3 mutations with VRF